Abstract
Merkel cell carcinoma (MMC) is a rare cutaneous neuroendocrine cancer that has the potential to metastasize. However, brain metastasis is infrequent in this type of cancer. We presented a case of a 55-year-old female patient with MCC who had a skin lesion on her right thigh. The cancer had spread to the brain and caused the development of splenic nodules. The patient also experienced intractable headaches and right-sided body weakness, which mimicked the symptoms seen in stroke cases. This case highlights the unusual clinical features and emphasizes the need for further investigation and understanding of the behavior of MCC, particularly in relation to metastasis patterns and associated symptoms.