Association between obesity with disease-free survival and overall survival in triple-negative breast cancer: A meta-analysis

肥胖与三阴性乳腺癌患者的无病生存期和总生存期之间的关联:一项荟萃分析

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Abstract

OBJECTIVE: To investigate the relationship between obesity and disease-free survival (DFS) and overall survival (OS) of triple-negative breast cancer. METHODS: Citations were searched in PubMed, Cochrane Library, and Web of Science. Random effect model meta-analysis was conducted by using Revman software version 5.0, and publication bias was evaluated by creating Egger regression with STATA software version 12. RESULTS: Nine studies (4412 patients) were included for DFS meta-analysis, 8 studies (4392 patients) include for OS meta-analysis. There were no statistical significances between obesity with DFS (P = .60) and OS (P = .71) in triple-negative breast cancer (TNBC) patients. CONCLUSION: Obesity has no impact on DFS and OS in patients with TNBC.

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