Abstract
Cardiac amyloidosis is a rare but increasingly recognized cause of heart failure, often underdiagnosed until later stages of the disease. This report describes a case of transthyretin amyloidosis (ATTR) in a 68-year-old male patient with a significant medical history of rheumatoid arthritis (RA), a combination seldom documented in the literature. The patient presented with progressive symptoms of heart failure, and diagnostic testing confirmed ATTR cardiac amyloidosis through pyrophosphate (PYP) scanning. This case highlights the clinical presentation, diagnostic process, and management of cardiac amyloidosis while exploring a potential link between RA and amyloid deposition. Early recognition of cardiac amyloidosis is crucial for improving outcomes, especially in patients with coexisting systemic inflammatory conditions like RA.