Abstract
After plasma cell neoplasia, osteosarcoma is the most common primary bone tumor which accounts for 20% of all sarcomas. A malignant tumor is characterized by the formation of bone or osteoid by tumor cells. Long bones are the most common site of involvement. In the jaw bones, approximately 5% of involvement with an incidence of 1 in 1.5 million persons per year. It develops in a broad range of ages but is more common in the third and fourth decades, slightly more often in the mandible than in the maxilla. In this case report, a 24-year-old male patient reported a mass in the left mandible for the past 1 week which appeared after the third molar extraction. In the orthopantomogram, a loss of lamina dura and a change in the trabecular pattern was noted. Histopathological findings were suggestive of osteoblastic osteogenic sarcoma. The patient underwent a hemi-mandibulectomy followed by chemotherapy. The main aim of this case report was to focus on the importance of early diagnosis of this tumor based on clinical and radiographic examinations, particularly taking into account the fast progression and aggressiveness of this neoplasm.