Abstract
A 70-year-old man presented to our hospital with chest discomfort and epigastric pain. Echocardiography revealed a giant atrial myxoma in the right atrium with severe tricuspid regurgitation. The aortic valve was calcified, and severe aortic stenosis was observed. Coronary angiography revealed diffuse lesions in the right coronary artery. The myxoma was surgically excised, and the residual septal defect was repaired using autologous pericardium tissue. Tricuspid valve annuloplasty, aortic valve replacement, and coronary artery bypass grafting were then performed. Clinicians should be aware that myxomas can coexist with other cardiac diseases. Careful preoperative evaluation and surgical planning should be performed prior to urgent surgeries for myxomas.