Abstract
This report describes an uncommon tumor of the salivary glands, myoepithelioma, that primarily affects major and minor glands, with a notable predilection for the parotid gland. Typically benign, this tumor arises from aberrant myoepithelial cells situated between the basement membrane and acinar cells. Myoepitheliomas are considered a subset of pleomorphic adenomas, distinguished by excessive myoepithelial cell growth. Despite their initial discovery, the precise histopathological and immunohistochemical characteristics of these tumors remain elusive, posing a diagnostic challenge because of their complex nature. We discuss a case of a 42-year-old female who had a 2 x 2 cm lump in the right infra-auricular area. The lump was examined with ultrasonography (USG) and later surgically removed. The initial frozen section analysis indicated an oncocytic lesion, but further histopathological and immunohistochemical evaluations confirmed that it was a myoepithelioma of the parotid gland.