Abstract
Adult intussusception is an unusual condition that is infrequently associated with malignancy. We experienced a rare occurrence of ileocecal intussusception in a 31-year-old male, secondary to metastatic melanoma. The patient, with a medical history of scalp malignant melanoma treated surgically and with chemotherapy, presented with persistent lower abdominal pain. Diagnostic modalities, including computed tomography (CT) and colonoscopy, revealed ileocecal intussusception. Subsequent laparoscopic surgery and pathological examination identified metastatic melanoma as the etiological factor for the intussusception, leading to the surgical resection of the involved bowel segment. The postoperative period was marked by a smooth recovery with no complications. This case shows the importance of considering malignancy in the differential diagnosis of adult intussusception and underscores the urgency of surgical intervention in the management of such cases.