Follow-up study of anti-SARS-CoV-2 IgG antibody response in COVID-19 patients up to 6 months after infection

感染 COVID-19 患者 6 个月内抗 SARS-CoV-2 IgG 抗体反应的随访研究

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作者:Atalay Eray, Karamese Murat, Gumus Abdullah, Kahraman Ihsan, Kelesoglu Royca, Ozgur Didem, Tutuncu E Ediz

Discussion

High antibody levels in LI-positive patients correlated with some immunologic and biochemical parameters. Further studies should be performed to determine protective antibody levels against reinfection, how long protective titers last and the mechanisms by which COVID-19 symptoms, demographics and comorbidities may drive higher antibody levels.

Methods

A total of 156 participants were divided into two groups, Group 1: lung involvement (LI)-positive and Group 2: LI-negative. Biochemical parameters and anti-SARS-CoV-2 IgG antibody levels were measured.

Results

The results showed that mean levels of urea, LDH, CRP, ferritin, neutrophil count and D-dimer were significantly higher in the LI-positive group. In addition, mean antibody levels in the 3rd and 6th months were higher in the LI-positive group (p < 0.005).

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