Abstract
BACKGROUND: Seablite (Suaeda maritima) grows near mangrove forests and shrimp farms on the coast of the Thai Gulf and South of Thailand. Extracts of S. maritima root can relieve or treat some skin symptoms or diseases, and it can be possessed. METHODS: The aim of this study was to screen phytochemical constituents of S. maritima root extract (SMRE) to determine their in vitro biological activities related to skincare properties. RESULTS AND DISCUSSION: Qualitative phytochemical screening was positive for tannins and triterpenes. Total phenolic content (TPC) and total flavonoid content (TFC) were 191.3 ± 3.55 mg of GAE/g and 21.2 ± 2.09 mg of QE/g, respectively. SMRE inhibited the DPPH (2,2-Diphenyl-1-Picrylhydrazyl) radical (IC(50) = 0.25 ± 0.2 mg/ml) and lipid peroxidation (IC(50) = 2.61 ± 0.5 mg/ml). Human skin fibroblasts were increased by 26.58 ± 5.91% after treatment with SMRE (1.0 mg/ml) and exhibited wound healing capacity by narrowing the gap between skin fibroblast clusters. CONCLUSION: This study confirms the potential of SMRE for skincare protection which meets the need for traditional uses of plant-derived products for skincare applications.