Crystal structures of two thia-zolidinone derivatives bearing a tri-chloro-methyl substituent at the 2-position

两种噻唑烷酮衍生物的晶体结构,其2位带有三氯甲基取代基

阅读:1

Abstract

The title compounds 2-tri-chloro-methyl-3-phenyl-1,3-thia-zolidin-4-one (C(10)H(8)Cl(3)NOS), 1 and 3-(4-chloro-phen-yl)-2-tri-chloro-methyl-1,3-thia-zolidin-4-one (C(10)H(7)Cl(4)NOS) 2, are structurally related with one atom substitution difference in the para position of the benzene ring. In both structures, the thia-zolidinone ring adopts an envelope conformation with the S atom as the flap. The dihedral angles between the rings [48.72 (11) in 1 and 48.42 (9)° in 2] are very similar and the mol-ecules are almost superimposable. In both crystal structures, C-H⋯O 'head-to-tail' inter-actions between the chiral carbon atoms and the thia-zolidinone oxygen atoms result in infinite monochiral chains along the direction of the shortest unit-cell parameter, namely a in 1 and b in 2. C-H⋯π inter-actions between the thia-zolidinone carbon atom at the 4-position and the phenyl ring of the neighboring enanti-omer also help to stabilize the packing in each case, although the crystals are not isostructural.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。