Abstract
Platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) have been successfully used for inducing pulp regeneration in nonvital teeth. This case report highlights the difference between the outcomes of using PRF and PRP for pulp regeneration in a 13-year-old male patient, who had reported with endodontic treatment failure in his upper incisors. Gutta-percha and sealant were removed, and triple antibiotic paste (TAP) was placed in all the root canals and sealed with cavit. Subsequently, after TAP removal, 11 and 12 were treated with PRF, while 21 and 22 were treated with PRP. A resorbable matrix was placed over the PRF/PRP, over which mineral trioxide aggregate and glass ionomer cement were placed. After 2 years, all the upper maxillary incisors revealed dentinal wall thickening, root lengthening, and apical closure. However, apical bridge formation occurred only in incisors treated with PRF.