Abstract
Hereditary hemochromatosis (HH) is an inherited disorder, characterized by abnormal iron metabolism, resulting in systemic iron overload. The iron deposits in multiple organs including the liver, pancreas, heart, pituitary gland, joint, and skin and causes tissue damages leading to clinical manifestations. On the contrary, celiac disease (CD) is an autoimmune disorder associated with genetic and environmental triggers and frequently associated with iron deficiency. Additionally, pregnancy results in a physiological state of increased iron requirement due to volume expansion and fetus growth and development. We present an interesting case of a young female patient with concomitant CD and HH, who developed iron depletion following venesection which was further complicated by pregnancy and the postpartum period. This case highlights the rare co-existence of CD and HH, underscoring the diagnostic and therapeutic challenges in managing these concurrent conditions. Furthermore, it emphasizes the importance of patient education, clinical management, appropriate follow-up, and close monitoring of patients by multidisciplinary teams to establish the correct balance of body iron storage in order to prevent potential complications in a female patient of child-bearing age.