Coexistence of adeno-associated virus 2 with adenovirus 18 or herpesvirus may be associated with severe lingual papillomatosis in an immunocompromised individual

• Viral metagenomics analysis was conducted on samples from an HSCT recipient experiencing severe lingual papillomatosis. • Coexistence of AAV2 with AdV18 in fecal and HSV-1 in tissue samples was detected. • A second complete genome of AdV18 was obtained in this study and is available in public databases.