HLA Antigens in Omani Psoriasis Vulgaris Patients

阿曼寻常型银屑病患者的 HLA 抗原

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作者:Fatma Al-Mamari, Ali Al-Shirawi, Dd Banodkar, Suliman Al-Hashmi, Faiza Al-Yahyaae, Mathew Varghese, Ja Raeburn

Conclusion

Psoriasis does not appear to be associated universally with the same HLA antigens. The association of HLA-B52 with plaque psoriasis in Omani patients compares with the HLA-Cw6, -Bw57 and -DR7 preponderance in most other ethnic groups.

Methods

Fifty four Omani patients clinically diagnosed with plaque psoriasis attending the dermatology outpatient clinic in Al-Nahdah Hospital (the tertiary dermatology centre in Oman) were selected for HLA studies.

Results

HLA-B52 was present in 20.4% of patients 11/54 and in 5% of controls without psoriasis 5/100. For the association p was <0.004 and the relative risk (RR) was 4.86.

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