Abstract
Hemophilus parainfluenzae is a gram-negative coccobacillus that usually inhabits the respiratory tract. It is a causative agent of meningitis, usually in children. The author presents a case of a 34-year-old woman presented with fever, neck stiffness, and headache, two weeks after the diagnosis of coronavirus disease 2019 (COVID-19) infection. Her CT scan of the head showed sinusitis. CSF analysis showed monocytic pleocytosis. CSF cultures grew Hemophilus parainfluenzae. The patient improved on intravenous antibiotic ceftriaxone 2 grams every 12 hours. This article also provides a brief literature review of Hemophilus parainfluenzae infections associated with COVID-19 infection.