Abstract
Neurological symptoms that occur before the diagnosis of primary Sjögren's syndrome (PSS) can vary and affect either the central nervous system (CNS) or the peripheral nervous system (PNS). Aseptic meningitis, although rare, can be an initial central neurological sign of PSS. This case report describes a 54-year-old patient who was initially presented with aseptic meningitis and was subsequently diagnosed with PSS. The diagnosis was based on clinical features and the results of serum autoantibody tests. The patient did not undergo a minor salivary gland biopsy to confirm the diagnosis. Symptomatic management resulted in an improvement in the patient's condition.