Abstract
COVID-19 is emerging as a global pandemic and is a complex disease presenting with multi-organ involvement. Acute haemorrhagic necrotizing encephalopathy (AHNE) is a rarely reported phenomenon post-COVID-19 but is a rapidly progressing, fatal, haemorrhagic necrosis of the CNS parenchyma. Here, we present a very interesting case of a cirrhotic male patient with AHNE with COVID-19. Diagnosis of AHNE requires a multimodality approach and high index of suspicion in a patient suffering from SARS-CoV-2. Timely intervention and diagnosis may lead to a favourable outcome in the diagnosed cases. Future detailed studies in this direction may give an insight into this rare but important disease entity.