Synthesis of Fluorinated Amines: A Personal Account

氟化胺的合成:个人经验分享

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Abstract

This Account highlights the recent contributions made by our laboratory in the development of novel strategies to synthesize fluorinated amines. These strategies allow the practitioner to efficiently access carbamoyl fluorides, thiocarbamoyl fluorides as well as trifluoromethylamines using CO(2) or CS(2) as benign C1 sources. In addition, a novel N(SCF(3))CF(3) moiety was synthesized. Noteworthy, we demonstrated that this reagent could also be used in radical- or electrophilic-based trifluoromethylthiolation reactions.

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