Metabolic Syndrome in Non-diabetic Stroke Patients

非糖尿病卒中患者的代谢综合征

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Abstract

Introduction Metabolic syndrome (MetS) encompasses a range of diverse conditions, such as hypertension, hyperglycemia, central obesity, dyslipidemia, and diabetes. MetS in non-diabetic elderly patients with acute ischemic stroke can worsen vascular damage and lead to worse outcomes, highlighting the significance of early detection. Objective The objective of this paper was to determine the frequency of MetS in non-diabetic elderly patients with acute ischemic stroke visiting a tertiary care hospital. Material and methods This study was carried out in the medical department of Dr. Ziauddin Hospital in Karachi, Pakistan for a duration of six months from June 20, 2023, to December 19, 2023, following the adoption of the synopsis. All patients meeting the specified criteria and attending Dr. Ziauddin Hospital in Karachi were enrolled in the research. Informed consent was obtained after a thorough description of the methods, possible dangers, and advantages of the study. Each patient underwent the metabolic assessment according to the International Diabetes Federation (IDF) criteria. Data collected was recorded in the provided proforma and electronically utilized for research endeavors. The analysis was conducted utilizing SPSS version 26.0 (IBM Corp., Armonk, NY). Descriptive statistics were computed, and the chi-square/Fisher's exact test was utilized for stratified analysis, with a p-value < 0.05 deemed significant. Result The study included patients aged between 65 and 90 years, with a median age of 74. Among the total population assessed, 133 individuals were male (76.4%) and 41 were female (23.6%). MetS was identified in 116 patients, representing 66.7% of the study population. Conclusion It is to be concluded that MetS was highly prevalent in non-diabetic elderly patients with acute ischemic stroke. This highlights a significant relationship between MetS and the occurrence of cerebrovascular accidents in this demographic. Further exploration and potential interventions targeting MetS in this population could be beneficial for improving health outcomes.

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