Abstract
COVID-19, a novel pathogen that emerged in late 2019, has the potential to cause pneumonia with unique variants upon infection. Hence, the development of efficient diagnostic systems is crucial in accurately identifying infected patients and effectively mitigating the spread of the disease. However, the system poses several challenges because of the limited availability of labeled data, distortion, and complexity in image representation, as well as variations in contrast and texture. Therefore, a novel two-phase analysis framework has been developed to scrutinize the subtle irregularities associated with COVID-19 contamination. A new Convolutional Neural Network-based STM-BRNet is developed, which integrates the Split-Transform-Merge (STM) block and Feature map enrichment (FME) techniques in the first phase. The STM block captures boundary and regional-specific features essential for detecting COVID-19 infectious CT slices. Additionally, by incorporating the FME and Transfer Learning (TL) concept into the STM blocks, multiple enhanced channels are generated to effectively capture minute variations in illumination and texture specific to COVID-19-infected images. Additionally, residual multipath learning is used to improve the learning capacity of STM-BRNet and progressively increase the feature representation by boosting at a high level through TL. In the second phase of the analysis, the COVID-19 CT scans are processed using the newly developed SA-CB-BRSeg segmentation CNN to accurately delineate infection in the images. The SA-CB-BRSeg method utilizes a unique approach that combines smooth and heterogeneous processes in both the encoder and decoder. These operations are structured to effectively capture COVID-19 patterns, including region-homogenous, texture variation, and border. By incorporating these techniques, the SA-CB-BRSeg method demonstrates its ability to accurately analyze and segment COVID-19 related data. Furthermore, the SA-CB-BRSeg model incorporates the novel concept of CB in the decoder, where additional channels are combined using TL to enhance the learning of low contrast regions. The developed STM-BRNet and SA-CB-BRSeg models achieve impressive results, with an accuracy of 98.01%, recall of 98.12%, F-score of 98.11%, Dice Similarity of 96.396%, and IOU of 98.85%. The proposed framework will alleviate the workload and enhance the radiologist's decision-making capacity in identifying the infected region of COVID-19 and evaluating the severity stages of the disease.