Management of Radiation-induced Tissue Injuries: A Review of Current Treatment Strategies

放射性组织损伤的治疗:当前治疗策略综述

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Abstract

Although radiation therapy remains an integral component in cancer treatment, the sequela of tissue damage can result in long-term morbidity and mortality for patients. This article aimed to perform a comprehensive review of the current literature for both nonsurgical and surgical management strategies for radiation-induced injuries. METHODS: A literature search was performed on PubMed to review the current described management and treatment options for radiation-induced injuries. Patient demographics, medical diagnoses, complications, strategies of management care, and outcomes were reviewed. RESULTS: The most commonly described management options and reconstructive techniques of radiation wounds were analyzed and reported. CONCLUSIONS: Consideration of current techniques and outcomes in the management of radiation-induced wounds demonstrates that impaired wound healing remains a major problem. This literature review provides a detailed overview of the most frequently used therapies with recommendations for surgeons.

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