Abstract
Bipolar affective disorder (BD) involves episodes of severe mood disturbance of depression and hypomania or mania and can result from the sensitization produced by repeated episodes. The authors present a case report assessed in the outpatient department of psychiatry of a tertiary care hospital in western Maharashtra. The patient was a 70-year-old female with late-onset rapid cycling bipolar affective disorder with predominantly hypomanic and manic episodes and co-morbidities of hypothyroidism, type II diabetes mellitus, and bullous pemphigoid. She was treated successfully with Tab quetiapine 400 mg/day, Tab lithium 600 mg/day, and Tab thyroxine 125 μg/day with a favorable response.