Therapeutic Applications of Biogenic Silver Nanomaterial Synthesized from the Paper Flower of Bougainvillea glabra (Miami, Pink)

从九重葛纸花(迈阿密,粉红色)合成的生物银纳米材料的治疗应用

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作者:Mohammad Oves, Mohd Ahmar Rauf, Huda A Qari

Abstract

In this research, Bougainvillea glabra paper flower extract was used to quickly synthesize biogenic silver nanoparticles (BAgNPs) utilizing green chemistry. Using the flower extract as a biological reducing agent, silver nanoparticles were generated by the conversion of Ag+ cations to Ag0 ions. Data patterns obtained from physical techniques for characterizing BAgNPs, employing UV-visible, scattering electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering (DLS), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR), suggested that the nanoparticles have a spherical to oval form with size ranging from 10 to 50 nm. Spectroscopy and microscopic analysis were used to learn more about the antibacterial properties of the biologically produced BAgNPs from Bougainvillea glabra. Further, the potential mechanism of action of nanoparticles was investigated by studying their interactions in vitro with several bacterial strains and mammalian cancer cell systems. Finally, we can conclude that BAgNPs can be functionalized to dramatically inhibit bacterial growth and the growth of cancer cells in culture conditions, suggesting that biologically produced nanomaterials will provide new opportunities for a wide range of biomedical applications in the near future.

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