Abstract
AIM: This study aims to investigate the impact of temperature and atmospheric pressure on hospitalizations of patients with acute coronary syndrome (ACS). MATERIALS AND METHODS: This is a retrospective, observational, analytical study conducted in a single center, University Hospital Center "Mother Teresa," Tirana, Albania, in the period January-December 2018. This study included 1,165 patients with ACS, who performed urgent coronary angiography, from January 2018 to December 2018. Patients were diagnosed with ACS based on clinical and examination findings. The data were collected retrospectively using patient files. Baseline demographic, clinical, and procedural characteristics were collected. Data on atmospheric parameters, measured at the weather monitoring station, were obtained from the National Meteorological Service database. Measurements from the meteorological service provided values for each parameter: average daily temperature and atmospheric pressure in each country district. Atmospheric data measurements were taken for the day under review. The number of inhabitants for the respective districts is taken from the National Institute of Statistics (INSTAT). RESULTS: The study involved 1,165 patients, with a mean age of 63.1 years, ranging from 27 years to 89 years old. The majority of patients (78.6%) were male, while 21.4% were female. A statistically significant relationship was observed between seasonal changes in temperature and atmospheric pressure concerning the number of cases with ACS; the autumn season prevails with 27.9% of the total cases, followed by the spring season with 25.6%, the summer season with 24.2%, and winter season with 22.3% (p = 0.04). Additionally, significant changes in the average monthly values of temperature and atmospheric pressure were accompanied by a statistically significant increase in the number of cases as occurred in March-April and October-November (p ≤ 0.05). Most cases in the cold period (November-March) occurred on days with a change in temperature or atmospheric pressure with a statistically significant value of p < 0.05. CONCLUSION: An important relationship between seasonal, monthly, and daily changes in temperature and atmospheric pressure concerning the frequency of cases with ACS was observed.