Highly sensitive and selective detection of triphosgene with a 2-(2'-hydroxyphenyl)benzimidazole derived fluorescent probe

使用 2-(2'-羟基苯基)苯并咪唑衍生的荧光探针高灵敏度、高选择性地检测三光气

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作者:Wen-Zhu Bi, Yang Geng, Wen-Jie Zhang, Chen-Yu Li, Chu-Sen Ni, Qiu-Juan Ma, Su-Xiang Feng, Xiao-Lan Chen, Ling-Bo Qu

Abstract

In this work, a 2-(2'-hydroxyphenyl)benzimidazole derived fluorescent probe, 2-(2'-hydroxy-4'-aminophenyl)benzimidazole (4-AHBI), was synthesized and its fluorescent behavior toward triphosgene were evaluated. The results showed that 4-AHBI exhibited high sensitivity (limit of detection, 0.08 nM) and excellent selectivity for triphosgene over other acyl chlorides including phosgene in CH2Cl2 solution. Moreover, 4-AHBI loaded test strips were prepared for the practical sensing of triphosgene.

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