Abstract
In this work, an SEIR epidemic model with time-dependent transmission rate parameters for the multiple waves of COVID-19 infection was investigated. It is assumed that the transmission rate is determined by the superposition of the Gaussian pulses. The interaction of these dynamics is represented by recursive equations. Analysis of the overall dynamics of disease spread is determined by the effective reproduction number R(e)(t) produced throughout the infection period. The study managed to show the evolution of the epidemic over time and provided important information about the occurrence of multiple waves of COVID-19 infection in the world and Indonesia.