Abstract
This case report details the clinical presentation, diagnosis, and management of a 23-year-old female with a unique medical history, including psoriatic arthritis (PsA) and Takayasu arteritis (TAK) and ultimately presenting with acute ischemic young stroke. The patient initially presented with right hip and buttocks pain, multiple itchy skin lesions, and right sacroiliac joint pain in 2017. She was diagnosed with psoriatic arthritis and treated effectively, achieving complete remission by 2020. In August 2023, she presented with acute-onset neurological deficits and vascular symptoms leading to a diagnosis of TAK. This case highlights the challenges in diagnosing and managing a complicated case with overlapping autoimmune rheumatic diseases.