Abstract
This case report highlights the use of concentrated growth factor (CGF) in enhancing healing outcomes following endodontic periapical surgery. A 57-year-old female came with pain and swelling related to chronic periapical abscesses in her lower front teeth, necessitating surgical intervention. Apicectomy combined with CGF application was considered as a treatment option. CGF, an advanced autologous platelet concentrate, offers superior healing properties due to its natural composition and absence of anticoagulants, making it a favorable option over earlier techniques like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF). The surgical procedure, performed under an operating microscope, included meticulous debridement and the placement of a CGF membrane over the surgical site. Follow-up evaluations at six months and one year demonstrated significant healing, as evident clinically and radiographically. The present case indicated the potential of CGF as an effective adjunct in periapical surgery, promoting better healing and recovery in patients with challenging dental conditions. The findings support the growing interest in autologous biomaterials for regenerative dental procedures.