Brevibacillus Laterosporus Osteomyelitis and Hardware Infection in a Young, Immunocompetent Patient Successfully Treated by Oral Minocycline and Ceftriaxone via a Peripherally Inserted Central Catheter for Six Weeks

Brevibacillus laterosporus, an endospore-forming, aerobic, Gram-positive bacillus, is not only a potential biocontrol agent against plant pathogens but also a rare cause of human infection. Its pathogenicity in humans, especially in immunocompetent individuals, is still not fully understood. Skin infections caused by B. laterosporus are typically opportunistic, entering the skin through cuts, wounds, or other breaches in the skin's protective barrier, as in the case presented here. LEARNING POINTS: Skin infections caused by Brevibacillus laterosporus are generally considered opportunistic and more likely to occur in individuals with compromised immune systems or pre-existing skin conditions.Brevibacillus laterosporus infections in immunocompetent patients are exceedingly rare, and information about optimal treatment strategies is limited.