The Role of Obesity in the Poor Prognosis of COVID-19 Infection: A Review of 192 Patients

肥胖在 COVID-19 感染预后不良中的作用:192 例患者的回顾性研究

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Abstract

METHODS: We performed a retrospective study on all patients having COVID-19 infection and admitted to our institution between March 2020 and June 2021. Inclusion criteria included any patient over the age of 18 admitted to our institution's COVID-19 unit, or intensive care unit, with a positive COVID-19 PCR or positive COVID-19 serology (IgM). RESULTS: 192 patients met the inclusion criteria, with an average age of 62.68 years and a slight male predominance (64.58%). 76.04% of hospitalized patients and 80% of those admitted to the ICU were either overweight or obese. No statistically significant difference was found regarding the risk of in-hospital mortality and invasive ventilation. The same applies to the length of stay, admission to intensive care, O(2) needs, and for the various complications (all p values were >0.05). Patients with obesity type II and III have an increased risk of cardiac arrests and need for intubation and mechanical ventilation. CONCLUSION: Obesity tends to be a major risk factor for a pejorative evolution in the COVID-19 infection.

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