T-cell lymphocytopenia: An omnipresent predictor of morbidity and mortality in consequence of SARS-CoV disease and influenza A infections

T细胞淋巴细胞减少症:SARS-CoV疾病和甲型流感感染导致发病率和死亡率的普遍预测指标

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Abstract

PURPOSE OF THE RESEARCH: We proposed T-cell lymphocytopenia as a strategic predictor of serious coronavirus and influenza infections. Our preeminent goal was to determine whether a degree of T-cell lymphopenia would identify a distinct threshold cell count to differentiate between severe and non-severe infections. We codified an Index Severity Score to exploit an association between T-cell cytopenia and the grade of disease activity. PRINCIPAL RESULT: A T-cell count of 560 cells/uL or below signified a trend towards advanced disease.

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