A bio-fabricated tesla valves and ultrasound waves-powered blood plasma viscometer

生物制造的特斯拉阀门和超声波驱动的血浆粘度计

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作者:Wenqin Chen, Mao Xia, Wentao Zhu, Zhiye Xu, Bo Cai, Han Shen

Discussion

These results indicate that the TUBVP can serve as a point-of-care device in the ICU to evaluate the blood's viscosity and the anticoagulation treatment.

Methods

Here, we fabricate a novel digital device, called Tesla valves and ultrasound waves-powered blood plasma viscometer (TUBPV) which shows capacities in both viscosity measurement and coagulation monitoring.

Results

Based on the Hagen-Poiseuille equation, viscosity analysis can be faithfully performed by a video microscopy. Tesla-like channel ensured unidirectional liquid motion with stable pressure driven that was triggered by the interaction of Tesla valve structure and ultrasound waves. In few seconds the TUBPV can generate an accurate viscosity profile on clinic fresh blood samples from the flow time evaluation. Besides, Tesla-inspired microchannels can be used in the real-time coagulation monitoring.

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