Sustained hyperkalemia in an asymptomatic primary care patient. When to suspect familial pseudohyperkalemia

一名无症状的基层医疗患者出现持续性高钾血症。何时应怀疑家族性假性高钾血症

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Abstract

OBJECTIVES: Study and management of a case with elevated potassium levels without apparent clinical causes in successive follow-up visits. CASE PRESENTATION: We present the case of a primary care female patient who persistently exhibited elevated levels of potassium (5.3-5.9 mmol/L) in successive control laboratory tests, without an apparent clinical cause. The patient was ultimately referred to the Unit of Nephrology, where a potassium-low diet was indicated. Diet did not have any effect on potassium levels. After a thorough study, the cause of hyperkalemia could not be determined. CONCLUSIONS: The inconsistency between elevated potassium levels and the reason of consultation, and exclusion of other pre-analytical or pathological causes raised suspicion of familial pseudohyperkalemia. The sample was incubated at different times and temperatures to demonstrate their influence on levels of potassium in blood. Familial pseudohyperkalemia was established as the most probable diagnosis. Finally, the patient was discharged from the Unit of Nephrology and instructed to follow a normal diet.

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