Heterotrimeric G protein γ subunit DEP1 is involved in hydrogen peroxide signaling and promotes aerenchyma formation in rice roots

异源三聚体G蛋白γ亚基DEP1参与过氧化氢信号传导,并促进水稻根部通气组织的形成。

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Abstract

Heterotrimeric G-protein α and β-subunits regulate H(2)O(2)-mediated aerenchyma formation. The rice G-protein γ-subunit, dense and erect panicle 1 (DEP1), is known to interact with the α-subunit and regulate nitrogen utilization and yield. However, it is unclear whether DEP1 regulates cell death for aerenchyma formation in rice roots. Using wild-type WYJ8 and its transgenic line WYJ8(DEP1), we confirmed that DEP1 is involved in H(2)O(2)-mediated aerenchyma formation. The rates of aerenchyma formation varied in different parts of the roots in both varieties, with the highest rate in the 4-7 cm segments, reaching a plateau in the 7-8 cm segments. Compared with WYJ8, the aerenchyma area and H(2)O(2) content in WYJ8(DEP1) were increased by 55.98% and 53.37%, respectively; however, the responses of aerenchyma formation to exogenous H(2)O(2) were basically the same in the two varieties. Diphenylene iodonium (DPI) treatment had no effect on H(2)O(2) production and elimination processes in WYJ8, but significantly reduced the activity of the key enzyme that catalyzes H(2)O(2) biosynthesis in WYJ8(DEP1). Importantly, exogenous H(2)O(2) treatment did not offset the effect of the decrease in endogenous H(2)O(2) level caused by DPI on aerenchyma formation. These results indicated that DEP1 enhanced H(2)O(2) biosynthesis and promoted the cell death of the root cortex, thus contributing to aerenchyma development in WYJ8(DEP1).

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