The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro

Arginines within the third intracellular loop of the C. elegans OCTR-1 and human ADRA2A receptors are methylated by the human protein arginine methyltransferase PRMT5 in vitro . Methylation of these residues could serve to modulate receptor signaling in vivo .