Abstract
Abstract in English, Chinese Copper (Cu)-bearing stainless steel has testified its effectiveness to reduce the risk of bacterial infections. However, its antibacterial mechanism is still controversial. Therefore, three 430 ferritic stainless steels with different Cu contents are selected to conduct deeper research by the way of bacterial inactivation from two aspects of material and biology. Hereinto, electrochemical and antibacterial results show that the increase in Cu content simultaneously improves the corrosion resistance and antibacterial property of 430 stainless steel. In addition, it is found that Escherichia coli (E. coli) on the surface 430 Cu-bearing stainless steel by the dry method of inoculation possesses a rapid inactivation ability. X-ray photoelectron spectroscopy (XPS) aids with ion chelation experiments prove that Cu (I) plays a more crucial role in the contact-killing efficiency than Cu (II), resulting from more production of reactive oxygen species (ROS). 含铜不锈钢已被证实能够有效地降低细菌感染所带来的风险。然而, 关于其抗菌机制仍存在争议。因此, 我们选择3种不同铜含量的430铁素体不锈钢, 通过细菌灭活的方法, 从材料学和生物学两个方面进行深入的研究。电化学和抗菌实验结果表明, 铜含量的增加同时提高了430不锈钢的耐蚀性能和抗菌性能。此外, 通过干法接种技术发现大肠杆菌在430含铜不锈钢表面可以快速的被灭活。XPS结合离子螯合实验证明, 由于Cu (I)可以促进产生更多的活性氧(ROS), 因此在接触杀灭过程中Cu (I)比Cu (II)起着更为重要的作用。.