To Divide or Differentiate: It Is about Scaffolding

Arabidopsis plants have specific polarized proteins, BASL and POLAR, that regulate stomatal asymmetric cell division (ACD). Earlier work established that BASL recruits YODA kinase (MAPKKK4) to suppress stomatal ACD in postmitotic cells. Houbaert et al. (Nature 2018;563:574-578) recently showed that POLAR scaffolds BIN2/GSK3s to promote stomatal ACD in premitotic cells.