Secondary Amyloidosis of the Urinary Bladder Presenting As Urinary Retention

Bladder amyloidosis is a rare condition of insoluble extracellular protein deposition in the urinary bladder arising as a complication of underlying inflammation and immune dyscrasia. Diagnosis of bladder amyloidosis is done through cystoscopy and evidence of amyloid deposition on pathologic evaluation. Here, we present a case of secondary bladder amyloidosis presenting with acute urinary retention. After ruling out bladder malignancy, the patient was managed with suprapubic catheterization after failing beta-3 agonist therapy and clean intermittent catheterization.