Abstract
Background: Lipoma is one of the benign tumors that originate from adipose tissue, most likely in the neck, chest, back, shoulders, arms, and thighs. It is rare to find lipoma originating from submucosal adipose tissue. Colonic submucosal lipomas develop at frequency of 0.035%-4.4%. The incidence of submucosal colonic lipoma is 0.15% at colonoscopy. Intussusception is a common cause of bowel obstruction in children; however, it is rare in adults. Usually, it has a malignant background in adults. Case Presentation: A 43-year-old male presented to the hospital with a history of intermittent abdominal pain for 6 months. Pain is associated with alternating diarrhea and constipation. Physical examination showed left lower abdominal tenderness. CT scan of the abdomen showed sigmoid colo-colonic intussusception. Discussion: Colo-colonic intussusceptions account for 17% of all intestinal intussusceptions in adults, and it is most likely caused by malignant lesions rather than a submucosal lipoma. Conclusion: Submucosal lipoma is a rare cause of colo-colonic intussusceptions. It should be considered in differential diagnosis.