Abstract
Adult intussusception is an uncommon cause of bowel obstruction, accounting for less than 5% of cases, and is often linked to a pathological lead point. Among benign etiologies, colonic lipomas are rare but recognized causes. We report a case of a 52-year-old male patient who presented with an atypically prolonged one-week history of intermittent abdominal pain and nausea, without signs of overt obstruction. Physical examination revealed abdominal tenderness and hypoactive bowel sounds. Contrast-enhanced computed tomography (CT) demonstrated a rare cecocolic intussusception with a fat-density mass in the transverse colon, suggestive of a colonic lipoma. Exploratory laparotomy confirmed a large submucosal lipoma acting as the lead point. Given the patient's age and the imaging ambiguity regarding malignancy, a limited right hemicolectomy was performed. Histopathology confirmed a benign submucosal lipoma. Postoperative recovery was uneventful, and the patient remained symptom-free at three-month follow-up. This case highlights an atypical, subacute presentation of adult intussusception caused by a colonic lipoma. It underscores the diagnostic utility of CT imaging and the rationale for an oncologically safe resection in uncertain cases, even with benign imaging features.