Abstract
OBJECTIVES: Pertussis is a globally endemic infectious disease, with recent resurgences reported even in countries with high vaccination coverage. This study aimed to analyze the epidemiological characteristics of pertussis cases in the Capital Region of Republic of Korea in 2024 and provide foundational data for future disease control strategies. METHODS: We conducted a descriptive analysis of confirmed pertussis cases reported to the Infectious Disease Information System between January 1 and December 31, 2024. The variables analyzed included demographic characteristics, monthly and regional incidence, clinical symptoms, vaccination status, and outbreak distribution by location and region. RESULTS: In 2024, a total of 26,239 pertussis cases were reported cases in the Capital Region of Republic of Korea, representing a significant increase from the previous year. Most cases occurred in children and adolescents, with a notable surge starting in May and peaking during the summer. Respiratory symptoms were observed in 99.1% of the cases; of these, 23.5% had paroxysmal cough and 76.4% had mild or atypical cough. A total of 1,556 outbreaks involving 9,657 related cases were identified, with 98.8% linked to school settings. CONCLUSIONS: The recent increase in pertussis cases in the capital region appears to be driven by a combination of factors, including transmission among children and adolescents and school-based outbreaks. Considering the 2024 domestic trends and international developments, a systematic revision of national pertussis prevention and response strategies is urgently needed.