Abstract
Takotsubo cardiomyopathy is a rare, reversible form of acute left ventricular dysfunction triggered by a catecholamine surge in response to severe stress. We report the case of a 42-year-old woman who developed acute ECG changes, regional wall motion abnormalities with apical ballooning, and markedly elevated cardiac biomarkers 72 hours after resection of a cerebellopontine angle meningioma. Coronary angiography excluded obstructive coronary disease, and supportive management led to rapid recovery of ventricular function. This case highlights the need for early recognition of perioperative Takotsubo cardiomyopathy in neurosurgical patients because its clinical presentation can mimic acute coronary syndrome and because misdiagnosis may lead to inappropriate antithrombotic management. We recommend prompt echocardiography and coronary angiography when clinically feasible, multidisciplinary discussion, and tailored hemodynamic support in suspected cases.