Abstract
Situs inversus (SI) is a rare congenital disorder in which the abdominal and thoracic organs create a mirror image orientation of their typical anatomical positions. In this article, we present the case of a 49-year-old female individual who underwent a scheduled laparoscopic cholecystectomy (LC) due to postprandial colic pain in the epigastrium. A prior ultrasound examination, conducted a year earlier, revealed the presence of small gallstones within the gallbladder, and a follow-up preoperative ultrasound suggested the possibility of SI, though the diagnosis was ruled out by a third ultrasound. Standard LC was commenced with umbilical trocar placement; however, SI was confirmed, and trocar placement was mirrored to the left side. Accurate preoperative diagnosis is crucial for surgical planning and to ensure patient safety. Performing an LC on a patient with SI poses unique challenges and requires heightened surgical skills and adaptability by the operating surgeon with extensive anatomical knowledge to mitigate risks and optimize patient outcomes.