Abstract
Leiomyoma is defined as a benign proliferation of smooth muscle cells. Smooth muscle tumors are considered the second-most common mesenchymal neoplasm in the gastrointestinal (GI) tract. It typically occurs incidentally in the large bowel. Colonic leiomyomas are considered to be very rare and commonly found in the descending or sigmoid colon. We report a case of a 32-year-old woman with no previous medical illness who presented with on-and-off abdominal pain, was found to have a left colonic mass, and underwent laparoscopic left hemicolectomy, with the final histopathological assessment revealing smooth muscle leiomyoma.