Abstract
Acute pancreatitis (AP) is a well-known cause of hospitalization and can lead to numerous complications. One such rare complication is portal vein thrombosis (PVT), defined as obstruction of the portal vein due to a thrombus within the vessel. The development of PVT in patients without any predisposing risk factors may pose a significant diagnostic challenge and can lead to delays in diagnosis and treatment. Here, we present the case of a patient with no past medical history and no significant risk factors, who insidiously developed PVT after initially being admitted with AP. The purpose of this case is to highlight this atypical presentation in the absence of risk factors and to emphasize the importance of repeat imaging in identifying PVT, allowing for rapid initiation of anticoagulation to improve long-term patient outcomes.