Diagnostic Accuracy of a Questionnaire Screening Test in Assessing the Prevalence of Hidradenitis Suppurativa in Sydney, Australia

问卷筛查测试在评估澳大利亚悉尼化脓性汗腺炎患病率中的诊断准确性

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Abstract

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with significant patient burden and impact on quality of life. Australia has a population of over 25 million people, with an estimated 29% of people born overseas. Previous studies have estimated the prevalence of HS in Australia to be approximately 0.67%, but methodological issues limit the accuracy of this estimate. This study was a part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative, aiming to objectively quantify the prevalence of HS in Australia. METHODS: The methodology followed the previously published GHiSA methodology. A validated questionnaire was used to identify patients likely to have a diagnosis of HS. Screen-positive patients as well as a selection of screen-negative patients underwent clinical examination by a single physician experienced in the identification, diagnosis and management of HS to further validate the sensitivity and specificity of the questionnaire. RESULTS: A total of 1,657 eligible healthy accompanying adults were approached, of whom 1,002 consented for inclusion in the study (60.5%). A total of 9 were survey screen-positive for HS, representing a prevalence of 0.9% (95% CI: 0.5%-1.7%). CONCLUSIONS: This single tertiary referral center study identified an HS prevalence of 0.9% in Australia. The methods address the deficiencies in other methodologies and provide insight into the prevalence of HS globally as part of the GHiSA initiative.

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