Thyroid Malignancy with Tracheal Invasion: Evaluating Process and Outcomes

甲状腺恶性肿瘤侵犯气管:过程与结果评估

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Abstract

AIM: Tracheal invasion by thyroid cancers poses significant surgical challenges. In this case series, we present our experience of tracheal resection and reconstruction in eight patients. This study highlights the importance of a coordinated multidisciplinary approach and technique of partial tracheal resection as well as evaluates the outcomes of this complex surgical intervention. MATERIALS AND METHODS: This study is the retrospective analysis of prospectively maintained data base of Thyroid cancer. RESULTS: The tracheal resection and reconstruction was performed in eight patients, including five males and three females, with a median age of 51 years. Seven patients had papillary thyroid carcinoma, while one had medullary thyroid carcinoma. Seven underwent partial tracheal resection, and one had full-thickness resection with anastomosis, achieving negative margins in all cases. No major complications related to tracheal resection and reconstruction except one patient had mortality due to carotid blow out. Over a median follow-up of 24 months (12-28 months), 6 patients remained disease-free. CONCLUSION: Tracheal resection and reconstruction for thyroid cancer with tracheal invasion is a viable approach, offering favourable outcomes in carefully selected patients. While the procedure is associated with inherent risks, a multidisciplinary approach and technical expertise are pivotal in minimizing complications and optimizing survival.

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