Visual Integration of Genome-Wide Association Studies and Differential Expression Results with the Hidecan R Package

利用 Hidecan R 包实现全基因组关联研究和差异表达结果的可视化整合

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Abstract

BACKGROUND/OBJECTIVES: We present hidecan, an R package for generating visualisations that summarise the results of one or more genome-wide association studies (GWAS) and differential expression analyses, as well as manually curated candidate genes, e.g., extracted from the literature. This tool is applicable to all ploidy levels; we notably provide functionalities to facilitate the visualisation of GWAS results obtained for autotetraploid organisms with the GWASpoly package. RESULTS: We illustrate the capabilities of hidecan with examples from two autotetraploid potato datasets. CONCLUSIONS: The hidecan package is implemented in R and is publicly available on the CRAN repository and on GitHub. A description of the package, as well as a detailed tutorial, is made available alongside the package. It is also part of the VIEWpoly tool for the visualisation and exploration of results from polyploids computational tools.

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