Abstract
This report presents a case of a 57-year-old woman with protein C deficiency who developed a renal artery covered stent infection owing to Staphylococcus lugdunensis infection, resulting in a pararenal aortic pseudoaneurysm. She had previously undergone a thrombectomy and covered stent placement owing to renal artery thrombosis before developing recurrent thrombosis, infection, and a pseudoaneurysm. She required open repair with nephrectomy, aortic debridement, rifampin-soaked Dacron patch angioplasty, and a prolonged antibiotic course. Her anatomy and clinical presentation precluded endovascular options, highlighting the complexity of such cases. This report emphasizes the need for heightened awareness of rare stent infections, individualized surgical planning, and the importance of antibiotic prophylaxis during endovascular procedures.