Abstract
The Renew Procedure is an elective comprehensive surgical and prosthetic intervention designed to address severe oral health issues, particularly periodontitis, and by systematically eliminating sources of chronic inflammation in the mouth, overall systemic health may improve. Additionally, restoring functionality and aesthetics to the mouth can significantly enhance a patient's quality of life. This study investigates whether improvements in oral health via the Renew Procedure correlate with measurable reductions in depressive symptoms, as assessed using the Patient Health Questionnaire-9 (PHQ-9), a pre- and post-operative assessment administered to patients undergoing full-mouth rehabilitation with the Renew Procedure. The results indicate a statistically significant decrease in PHQ-9 scores, suggesting that the intervention may contribute to improved mental health outcomes. These findings support the need for integrated healthcare approaches that recognize the interconnections between oral health, systemic inflammation, and mental well-being.